CCR8 Antikörper

Produktnummer ABIN2463725

Produktdetails anti-CCR8 Antikörper

Target: CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCR8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CCR8.

Anwendungsinformationen

Applikationshinweise: CCR8 antibody can be used for detection of CCR8 by ELISA at 1:62500. CCR8 antibody can be used for detection of CCR8 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CCR8 antibody at -20 °C.

Details zu CCR8

Target: CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))

Andere Bezeichnung: CCR8 (CCR8 Produkte)

Synonyme: CC-CKR-8 antikoerper, CCR-8 antikoerper, CDw198 antikoerper, CKRL1 antikoerper, CMKBR8 antikoerper, CMKBRL2 antikoerper, CY6 antikoerper, GPRCY6 antikoerper, TER1 antikoerper, C-C antikoerper, C-C CKR-8 antikoerper, CKR-8 antikoerper, Cmkbr8 antikoerper, mCCR8 antikoerper, C-C motif chemokine receptor 8 antikoerper, chemokine (C-C motif) receptor 8 antikoerper, CCR8 antikoerper, Ccr8 antikoerper

Hintergrund: CCR8 is a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. Its gene is located at the chemokine receptor gene cluster region.

Molekulargewicht: 41 kDa

Gen-ID: 1237

NCBI Accession: NP_005192

UniProt: P51685