PAXIP1 Antikörper
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- Target Alle PAXIP1 Antikörper anzeigen
- PAXIP1 (PAX Interacting (With Transcription-Activation Domain) Protein 1 (PAXIP1))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PAXIP1 Antikörper ist unkonjugiert
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Applikation
- ELISA, Western Blotting (WB)
- Aufreinigung
- Antibody is purified by peptide affinity chromatography method.
- Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PAXIP1.
- Top Product
- Discover our top product PAXIP1 Primärantikörper
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- Applikationshinweise
- PAXIP1 antibody can be used for detection of PAXIP1 by ELISA at 1:62500. PAXIP1 antibody can be used for detection of PAXIP1 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Konzentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Handhabung
- As with any antibody avoid repeat freeze-thaw cycles.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store PAXIP1 antibody at -20 °C.
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- Target
- PAXIP1 (PAX Interacting (With Transcription-Activation Domain) Protein 1 (PAXIP1))
- Andere Bezeichnung
- PAXIP1 (PAXIP1 Produkte)
- Synonyme
- CAGF29 antikoerper, PACIP1 antikoerper, PAXIP1L antikoerper, PTIP antikoerper, TNRC2 antikoerper, wu:fa04b06 antikoerper, zgc:92593 antikoerper, cagf28 antikoerper, cagf29 antikoerper, k14 antikoerper, pacip1 antikoerper, paxip1l antikoerper, ptip antikoerper, tnrc2 antikoerper, D5Ertd149e antikoerper, PAX interacting protein 1 antikoerper, PAX interacting (with transcription-activation domain) protein 1 antikoerper, PAX interacting protein 1 L homeolog antikoerper, PAXIP1 antikoerper, paxip1 antikoerper, paxip1.L antikoerper, Paxip1 antikoerper
- Hintergrund
- PAXIP1 functions as a key component of the DNA damage response, and phosphoserine or phosphothreonine-specific binding modules. PAXIP1 recognizes substrates phosphorylated by the kinases ataxia telangiectasia-mutated (ATM), ataxia telangiectasia and RAD3-related (ATR) in response to gamma irradiation. It may play a role in PAX2-dependent transcriptional regulation. PAXIP1 plays a role in early development, most probably in cell proliferation.
- Molekulargewicht
- 74 kDa
- Gen-ID
- 22976
- UniProt
- Q6ZW49
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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