MBNL2 Antikörper

Produktnummer ABIN2463438

Produktdetails anti-MBNL2 Antikörper

Target: MBNL2 (Muscleblind-Like 2 (MBNL2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MBNL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MBNL2.

Anwendungsinformationen

Applikationshinweise: MBNL2 antibody can be used for detection of MBNL2 by ELISA at 1:1562500. MBNL2 antibody can be used for detection of MBNL2 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store MBNL2 antibody at -20 °C.

Details zu MBNL2

Target: MBNL2 (Muscleblind-Like 2 (MBNL2))

Andere Bezeichnung: MBNL2 (MBNL2 Produkte)

Synonyme: 1110002M11Rik antikoerper, AI047808 antikoerper, AI837313 antikoerper, AI849185 antikoerper, AL118326 antikoerper, MBLL antikoerper, R75232 antikoerper, mKIAA4072 antikoerper, wu:fj89c04 antikoerper, MBLL39 antikoerper, PRO2032 antikoerper, muscleblind like splicing factor 2 antikoerper, muscleblind-like splicing regulator 2 antikoerper, muscleblind like splicing regulator 2 antikoerper, Mbnl2 antikoerper, mbnl2 antikoerper, MBNL2 antikoerper

Hintergrund: MBNL2 is a C3H-type zinc finger protein, which is similar to the Drosophila melanogaster muscleblind B protein.MBNL2 is a RNA-binding protein that binds to 5'ACACCC-3' core sequence. It binds to CUG triplet repeat expansion in myotonic dystrophy muscle cells by sequestering the target RNAs. MBNL2 seems to regulate expression and localization of ITGA3 by transporting it from the nucleus to cytoplasm. It may play a role in myotonic dystrophy pathophysiology (DM).

Molekulargewicht: 28 kDa

Gen-ID: 10150

NCBI Accession: NP_005748

UniProt: O95205