MBNL2 Antikörper (Middle Region)

Produktnummer ABIN2784554

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch MBNL2 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio) und Pferd.

Kurzübersicht für MBNL2 Antikörper (Middle Region) (ABIN2784554)

Target: MBNL2 (Muscleblind-Like 2 (MBNL2))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio), Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MBNL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MBNL2 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: MBNL2 Antibody - middle region

Sequenz: ENGRVIACFD SLKGRCSREN CKYLHPPTHL KTQLEINGRN NLIQQKTAAA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against MBNL2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MBNL2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8105855

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu MBNL2

Target: MBNL2 (Muscleblind-Like 2 (MBNL2))

Andere Bezeichnung: MBNL2

Hintergrund:

Background Information: MBNL2 is a C3H-type zinc finger protein, which is similar to the Drosophila melanogaster muscleblind B protein.MBNL2 is a RNA-binding protein that binds to 5'ACACCC-3' core sequence. It binds to CUG triplet repeat expansion in myotonic dystrophy muscle cells by sequestering the target RNAs. MBNL2 seems to regulate expression and localization of ITGA3 by transporting it from the nucleus to cytoplasm. It may play a role in myotonic dystrophy pathophysiology (DM).

Gene Name: Muscleblind-like splicing regulator 2

Alternative Symbols: MBLL, MBLL39, PRO2032

Protein Name: Muscleblind-like 2 (Drosophila), isoform CRA_b EMBL EAX08969.1

Molekulargewicht: 28kDa

Gen-ID: 10150

NCBI Accession: NP_005748

UniProt: O95205