SEPN1 Antikörper
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- Target Alle SEPN1 Antikörper anzeigen
- SEPN1 (Selenoprotein N, 1 (SEPN1))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SEPN1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Aufreinigung
- Antibody is purified by peptide affinity chromatography method.
- Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SEPN1.
- Top Product
- Discover our top product SEPN1 Primärantikörper
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- Applikationshinweise
- SEPN1 antibody can be used for detection of SEPN1 by ELISA at 1:1562500. SEPN1 antibody can be used for detection of SEPN1 by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Konzentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Handhabung
- As with any antibody avoid repeat freeze-thaw cycles.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store SEPN1 antibody at -20 °C.
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- Target
- SEPN1 (Selenoprotein N, 1 (SEPN1))
- Andere Bezeichnung
- SEPN1 (SEPN1 Produkte)
- Synonyme
- CFTD antikoerper, MDRS1 antikoerper, RSMD1 antikoerper, RSS antikoerper, SELN antikoerper, 1110019I12Rik antikoerper, AI414492 antikoerper, SePN antikoerper, cb686 antikoerper, wu:fb06g01 antikoerper, wu:fb73d02 antikoerper, wu:fv41b08 antikoerper, zgc:101091 antikoerper, selenoprotein N antikoerper, SELENON antikoerper, Selenon antikoerper, selenon antikoerper
- Hintergrund
- SEPN1 is a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. Mutations in SEPN1 gene cause the classical phenotype of multiminicore disease and congenital muscular dystrophy with spinal rigidity and restrictive respiratory syndrome.This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Mutations in this gene cause the classical phenotype of multiminicore disease and congenital muscular dystrophy with spinal rigidity and restrictive respiratory syndrome. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
- Molekulargewicht
- 58 kDa
- Gen-ID
- 57190
- NCBI Accession
- NP_996809
- Pathways
- Skeletal Muscle Fiber Development
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