ZMPSTE24 Antikörper

Produktnummer ABIN2462996

Produktdetails anti-ZMPSTE24 Antikörper

Target: ZMPSTE24 (Zmpste24) (Zinc Metalloproteinase, Ste24 (Zmpste24))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZMPSTE24 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ZMPSTE24.

Anwendungsinformationen

Applikationshinweise: ZMPSTE24 antibody can be used for detection of ZMPSTE24 by ELISA at 1:312500. ZMPSTE24 antibody can be used for detection of ZMPSTE24 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store ZMPSTE24 antibody at -20 °C.

Details zu ZMPSTE24

Target: ZMPSTE24 (Zmpste24) (Zinc Metalloproteinase, Ste24 (Zmpste24))

Andere Bezeichnung: ZMPSTE24 (Zmpste24 Produkte)

Synonyme: DDBDRAFT_0189115 antikoerper, DDBDRAFT_0237846 antikoerper, DDB_0189115 antikoerper, DDB_0237846 antikoerper, F2N1.21 antikoerper, F2N1_21 antikoerper, STE24 antikoerper, FACE-1 antikoerper, FACE1 antikoerper, HGPS antikoerper, PRO1 antikoerper, Ste24p antikoerper, A530043O15Rik antikoerper, D030046F19 antikoerper, Face-1 antikoerper, MADB antikoerper, fi45a02 antikoerper, wu:fi45a02 antikoerper, zgc:55655 antikoerper, zinc metallopeptidase STE24 antikoerper, zinc metallopeptidase STE24 L homeolog antikoerper, CAAX prenyl protease antikoerper, Peptidase family M48 family protein antikoerper, zinc metallopeptidase, STE24 antikoerper, zinc metallopeptidase, STE24 homolog antikoerper, ZMPSTE24 antikoerper, zmpste24.L antikoerper, zmpste24 antikoerper, ATSTE24 antikoerper, Zmpste24 antikoerper

Hintergrund: ZMPSTE24 is a member of the peptidase M48A family. This protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in ZMPSTE24 gene have been associated with mandibuloacral dysplasia and restrictive dermopathy.The protein encoded by this gene is a zinc metalloprotease similar to yeast Ste24p. It is an integral membrane protein belonging to peptidase family M48 and is found in the endoplasmic reticulum and possibly in the Golgi compartment. It is thought to be involved in the proteolytic processing of farnesylated proteins.

Molekulargewicht: 55 kDa

Gen-ID: 10269

NCBI Accession: NP_005848

UniProt: O75844