COX15 Antikörper

Produktnummer ABIN2462983

Produktdetails anti-COX15 Antikörper

Target: COX15 (Cytochrome C Oxidase Assembly Homolog 15 (COX15))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COX15 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Aufreinigung: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human COX15.

Anwendungsinformationen

Applikationshinweise: COX15 antibody can be used for detection of COX15 by ELISA at 1:62500. COX15 antibody can be used for detection of COX15 by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store COX15 antibody at -20 °C.

Details zu COX15

Target: COX15 (Cytochrome C Oxidase Assembly Homolog 15 (COX15))

Andere Bezeichnung: COX15 (COX15 Produkte)

Synonyme: COX15 antikoerper, wu:fa18g06 antikoerper, zgc:56240 antikoerper, zgc:77422 antikoerper, 2900026G05Rik antikoerper, CEMCOX2 antikoerper, COX15, cytochrome c oxidase assembly homolog antikoerper, COX15 homolog, cytochrome c oxidase assembly protein (yeast) antikoerper, COX15 cytochrome c oxidase assembly homolog antikoerper, cytochrome c oxidase assembly homolog 15 (yeast) antikoerper, cytochrome c oxidase assembly protein 15 antikoerper, cytochrome c oxidase assembly protein COX15 homolog antikoerper, COX15 antikoerper, Cox15 antikoerper, cox15 antikoerper, LOC100410987 antikoerper, LOC100599631 antikoerper

Hintergrund: Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be essential for the biogenesis of COX formation and may function in the hydroxylation of heme O, according to the yeast mutant studies. This protein is predicted to contain 5 transmembrane domains localized in the mitochondrial inner membrane.Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be essential for the biogenesis of COX formation and may function in the hydroxylation of heme O, according to the yeast mutant studies. This protein is predicted to contain 5 transmembrane domains localized in the mitochondrial inner membrane. Alternative splicing of this gene generates several transcript variants diverging in the 3' region including alternate poly A sites. In total, 2 different isoforms are encoded by these variants.

Molekulargewicht: 44 kDa, 46 kDa

Gen-ID: 1355

NCBI Accession: NP_004367