PPFIBP1 Antikörper

Produktnummer ABIN2462533

Produktdetails anti-PPFIBP1 Antikörper

Target: PPFIBP1 (PTPRF Interacting Protein, Binding Protein 1 (Liprin beta 1) (PPFIBP1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPFIBP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PPFIBP1.

Anwendungsinformationen

Applikationshinweise: PPFIBP1 antibody can be used for detection of PPFIBP1 by ELISA at 1:312500. PPFIBP1 antibody can be used for detection of PPFIBP1 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store PPFIBP1 antibody at -20 °C.

Details zu PPFIBP1

Target: PPFIBP1 (PTPRF Interacting Protein, Binding Protein 1 (Liprin beta 1) (PPFIBP1))

Andere Bezeichnung: PPFIBP1 (PPFIBP1 Produkte)

Synonyme: liprin-beta-1 antikoerper, L2 antikoerper, SGT2 antikoerper, hSGT2 antikoerper, hSgt2p antikoerper, 4632409B19Rik antikoerper, AW214454 antikoerper, AW261454 antikoerper, PPFIA binding protein 1 antikoerper, PTPRF interacting protein, binding protein 1 (liprin beta 1) antikoerper, PTPRF interacting protein, binding protein 1 (liprin beta 1) S homeolog antikoerper, Ppfibp1 antikoerper, ppfibp1 antikoerper, ppfibp1.S antikoerper, PPFIBP1 antikoerper

Hintergrund: PPFIBP1 is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis.The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis. In vitro experiment demonstrated that the interaction inhibited the phosphorylation of this protein by protein kinase C and protein kinase CK2. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Molekulargewicht: 19 kDa, 113 kDa

Gen-ID: 8496

NCBI Accession: NP_803193