GSTM2 Antikörper

Produktnummer ABIN2462480

Produktdetails anti-GSTM2 Antikörper

Target: GSTM2 (Glutathione S-Transferase mu 2 (Muscle) (GSTM2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GSTM2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GSTM2.

Anwendungsinformationen

Applikationshinweise: GSTM2 antibody can be used for detection of GSTM2 by ELISA at 1:312500. GSTM2 antibody can be used for detection of GSTM2 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store GSTM2 antibody at -20 °C.

Details zu GSTM2

Target: GSTM2 (Glutathione S-Transferase mu 2 (Muscle) (GSTM2))

Andere Bezeichnung: GSTM2 (GSTM2 Produkte)

Synonyme: GSTA4 antikoerper, GST4 antikoerper, GSTM antikoerper, GSTM2-2 antikoerper, GTHMUS antikoerper, Gstb-2 antikoerper, Gstb2 antikoerper, GSTIV antikoerper, glutathione S-transferase mu 2 antikoerper, glutathione S-transferase mu 2 (muscle) antikoerper, glutathione S-transferase Mu 2 antikoerper, glutathione S-transferase, mu 2 antikoerper, glutathione S-transferase 2 antikoerper, Glutathione S-transferase 4 antikoerper, Gstm2 antikoerper, GSTM2 antikoerper, LOC100732167 antikoerper, gst2 antikoerper, gst-4 antikoerper

Hintergrund: At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. GSTM2 is a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione.Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs.

Molekulargewicht: 26 kDa

Gen-ID: 2946

NCBI Accession: NP_000839

UniProt: P28161

Pathways: Negative Regulation of Transporter Activity