Renin Antikörper

Produktnummer ABIN2462401

Produktdetails anti-Renin Antikörper

Target: Renin (REN)

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Renin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human REN.

Anwendungsinformationen

Applikationshinweise: REN antibody can be used for detection of REN by ELISA at 1:62500. REN antibody can be used for detection of REN by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store REN antibody at -20 °C.

Details zu Renin

Target: Renin (REN)

Andere Bezeichnung: REN (REN Produkte)

Synonyme: HNFJ2 antikoerper, RATRENAA antikoerper, RENAA antikoerper, Ren1 antikoerper, D19352 antikoerper, Ren antikoerper, Ren-1 antikoerper, Ren-A antikoerper, Ren1c antikoerper, Ren1d antikoerper, Rn-1 antikoerper, Rnr antikoerper, renin antikoerper, renin 1 structural antikoerper, REN antikoerper, Ren antikoerper, Ren1 antikoerper, ren antikoerper

Hintergrund: Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Mutations in this gene have been shown to cause familial hyperproreninemia.Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia.

Molekulargewicht: 45 kDa

Gen-ID: 5972

NCBI Accession: NP_000528

UniProt: P00797

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour