Aprataxin Antikörper

Produktnummer ABIN2462011

Produktdetails anti-Aprataxin Antikörper

Target: Aprataxin (APTX)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Aprataxin Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Western Blotting (WB)

Aufreinigung: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human APTX.

Anwendungsinformationen

Applikationshinweise: APTX antibody can be used for detection of APTX by ELISA at 1:1562500. APTX antibody can be used for detection of APTX by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store APTX antibody at -20 °C.

Details zu Aprataxin

Target: Aprataxin (APTX)

Andere Bezeichnung: APTX (APTX Produkte)

Synonyme: aptx antikoerper, APTX antikoerper, LOC100284636 antikoerper, APRATAXIN-like antikoerper, T10O8.20 antikoerper, T10O8_20 antikoerper, AOA antikoerper, AOA1 antikoerper, AXA1 antikoerper, EAOH antikoerper, EOAHA antikoerper, FHA-HIT antikoerper, 2410016G21Rik antikoerper, AA388047 antikoerper, aprataxin antikoerper, FHA-HIT antikoerper, APRATAXIN-like protein antikoerper, aprataxin L homeolog antikoerper, aptx antikoerper, APTX antikoerper, CpipJ_CPIJ001673 antikoerper, LOC100284636 antikoerper, aptx.L antikoerper, Aptx antikoerper

Hintergrund: APTX is a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. APTX may play a role in single-stranded DNA repair. Mutations in this gene have been associated with ataxia-ocular apraxia.This gene encodes a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. The encoded protein may play a role in single-stranded DNA repair. Mutations in this gene have been associated with ataxia-ocular apraxia. Multiple transcript variants encoding distinct isoforms have been identified for this gene, however, the full length nature of some variants has not been determined.This gene encodes a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. The encoded protein may play a role in single-stranded DNA repair. Mutations in this gene have been associated with ataxia-ocular apraxia. Multiple transcript variants encoding distinct isoforms have been identified for this gene, however, the full length nature of some variants has not been determined.

Molekulargewicht: 38 kDa, 20 kDa, 20 kDa, 29 kDa

Gen-ID: 54840

NCBI Accession: NP_778243

UniProt: Q6JV85

Pathways: DNA Reparatur, Chromatin Binding