NFIL3 Antikörper

Produktnummer ABIN2461756

Produktdetails anti-NFIL3 Antikörper

Target: NFIL3 (Nuclear Factor, Interleukin 3 Regulated (NFIL3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NFIL3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NFIL3.

Anwendungsinformationen

Applikationshinweise: NFIL3 antibody can be used for detection of NFIL3 by ELISA at 1:312500. NFIL3 antibody can be used for detection of NFIL3 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store NFIL3 antibody at -20 °C.

Details zu NFIL3

Target: NFIL3 (Nuclear Factor, Interleukin 3 Regulated (NFIL3))

Andere Bezeichnung: NFIL3 (NFIL3 Produkte)

Synonyme: e4bp4 antikoerper, il3bp1 antikoerper, nfil3a antikoerper, nf-il3a antikoerper, MGC107826 antikoerper, NFIL3 antikoerper, E4BP4 antikoerper, IL3BP1 antikoerper, NF-IL3A antikoerper, NFIL3A antikoerper, E4BP4-1 antikoerper, zgc:100867 antikoerper, AV225605 antikoerper, nuclear factor, interleukin 3 regulated antikoerper, nuclear factor, interleukin 3 regulated L homeolog antikoerper, nuclear factor, interleukin 3, regulated antikoerper, nfil3 antikoerper, NFIL3 antikoerper, Nfil3 antikoerper, nfil3.L antikoerper

Hintergrund: NFIL3 is a basic leucine zipper (bZIP) transcription factor that represses or activates transcription in non-osteoblastic cells. NFIL3 play a role in attenuation of PTH target gene transcription in osteoblasts. NFIL3 repression domain interacts specifically with the TBP binding repressor protein Dr1.Glucocorticoid-mediated upregulation of the bZIP transcriptional repressor gene, NFIL3, is dependent on [Ca2+]i levels, and correlates with Glucocorticoid-evoked apoptosis of Glucocorticoid-sensitive CEM-C7-14 cells. NFIL3 is involved in a distinct growth factor-regulated signaling pathway that is responsible for the survival of early B-cell progenitors, and whose alteration by E2A-HLF leads to childhood B lineage leukemia.

Molekulargewicht: 51 kDa

Gen-ID: 4783

NCBI Accession: NP_005375

UniProt: Q14211