NFIL3 Antikörper (Middle Region)

Produktnummer ABIN2777219

Der Kaninchen Polyklonal anti-NFIL3 Antikörper (ABIN2777219) detektiert spezifisch NFIL3 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Rind (Kuh), Schaf, Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio) und Kaninchen.

Kurzübersicht für NFIL3 Antikörper (Middle Region) (ABIN2777219)

Target: NFIL3 (Nuclear Factor, Interleukin 3 Regulated (NFIL3))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schaf, Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio), Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NFIL3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-NFIL3 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: NFIL3 Antibody - middle region

Sequenz: GYSHSPPLLQ VNRSSSNSPR TSETDDGVVG KSSDGEDEQQ VPKGPIHSPV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%, Zebrafish: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against NFIL3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NFIL3

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP31177-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu NFIL3

Target: NFIL3 (Nuclear Factor, Interleukin 3 Regulated (NFIL3))

Andere Bezeichnung: NFIL3

Hintergrund:

Background Information: NFIL3 is a basic leucine zipper (bZIP) transcription factor that represses or activates transcription in non-osteoblastic cells. NFIL3 play a role in attenuation of PTH target gene transcription in osteoblasts. NFIL3 repression domain interacts specifically with the TBP binding repressor protein Dr1.Glucocorticoid-mediated upregulation of the bZIP transcriptional repressor gene, NFIL3, is dependent on [Ca2+]i levels, and correlates with Glucocorticoid-evoked apoptosis of Glucocorticoid-sensitive CEM-C7-14 cells. NFIL3 is involved in a distinct growth factor-regulated signaling pathway that is responsible for the survival of early B-cell progenitors, and whose alteration by E2A-HLF leads to childhood B lineage leukemia.

Gene Name: Nuclear factor, interleukin 3 regulated

Alternative Symbols: E4BP4, IL3BP1, NFIL3A, NF-IL3A

Protein Name: Nuclear factor interleukin-3-regulated protein

Molekulargewicht: 51kDa

Gen-ID: 4783

NCBI Accession: NP_005375

UniProt: Q16649