NR2C1 Antikörper

Produktnummer ABIN2461692

Produktdetails anti-NR2C1 Antikörper

Target: NR2C1 (Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1))

Reaktivität: Human, Maus, Ratte, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NR2C1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NR2C1.

Anwendungsinformationen

Applikationshinweise: NR2C1 antibody can be used for detection of NR2C1 by ELISA at 1:62500. NR2C1 antibody can be used for detection of NR2C1 by western blot at 0.1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store NR2C1 antibody at -20 °C.

Details zu NR2C1

Target: NR2C1 (Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1))

Andere Bezeichnung: NR2C1 (NR2C1 Produkte)

Synonyme: TR2 antikoerper, NR2C1 antikoerper, dor2 antikoerper, tr2-11 antikoerper, xDOR2 antikoerper, DKFZp468M0512 antikoerper, si:dkey-183c16.2 antikoerper, zgc:110672 antikoerper, 4831444H07Rik antikoerper, 80.3 antikoerper, Eenr antikoerper, Tr2-11 antikoerper, Tr2 antikoerper, Psg4 antikoerper, TR2-11 antikoerper, PSG9 antikoerper, nr2c1 antikoerper, nuclear receptor subfamily 2 group C member 1 antikoerper, nuclear receptor subfamily 2 group C member 1 S homeolog antikoerper, nuclear receptor subfamily 2, group C, member 1 antikoerper, pregnancy specific beta-1-glycoprotein 4 antikoerper, nuclear receptor subfamily 2 group C member 1 L homeolog antikoerper, NR2C1 antikoerper, nr2c1.S antikoerper, nr2c1 antikoerper, Nr2c1 antikoerper, PSG4 antikoerper, nr2c1.L antikoerper

Hintergrund: The nuclear orphan receptors NR2C1 represses transcription and binds DNA as a homodimer. NR2C1 binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism. NR2C1 may function as a negative modulator to suppress androgen receptor function in prostate cancer. NR2C1 may exert an important repressor in regulating ER activity in mammary glands. The nuclear orphan receptors TR2 (NR2C1) and TR4 form a heterodimer that binds to the epsilon and gamma globin promoter DR1 sites

Molekulargewicht: 67 kDa

Gen-ID: 7181

NCBI Accession: NP_003288

UniProt: Q15625

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway