ID4 Antikörper

Produktnummer ABIN2461635

Produktdetails anti-ID4 Antikörper

Target: ID4 (Inhibitor of DNA Binding 4, Dominant Negative Helix-Loop-Helix Protein (ID4))

Reaktivität: Human, Maus, Ratte, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ID4 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Aufreinigung: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ID4.

Anwendungsinformationen

Applikationshinweise: ID4 antibody can be used for detection of ID4 by ELISA at 1:1562500. ID4 antibody can be used for detection of ID4 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store ID4 antibody at -20 °C.

Details zu ID4

Target: ID4 (Inhibitor of DNA Binding 4, Dominant Negative Helix-Loop-Helix Protein (ID4))

Andere Bezeichnung: ID4 (ID4 Produkte)

Synonyme: Idb4 antikoerper, bHLHb27 antikoerper, cb547 antikoerper, fb77d04 antikoerper, sb:cb547 antikoerper, wu:fb77d04 antikoerper, zgc:123214 antikoerper, bhlhb27 antikoerper, id4 antikoerper, id4a antikoerper, idb4 antikoerper, IDB4 antikoerper, inhibitor of DNA binding 4 antikoerper, inhibitor of DNA binding 4, HLH protein antikoerper, inhibitor of DNA binding 4, HLH protein S homeolog antikoerper, Id4 antikoerper, id4 antikoerper, id4.S antikoerper, ID4 antikoerper

Hintergrund: Transcription factors containing a basic helix-loop-helix (bHLH) motif regulate expression of tissue-specific genes in a number of mammalian and insect systems. DNA-binding activity of the bHLH proteins is dependent on formation of homo- and/or heterodimers. Dominant-negative HLH proteins encoded by Id-related genes, such as ID4, also contain the HLH-dimerization domain but lack the DNA-binding basic domain. Consequently, Id proteins inhibit binding to DNA and transcriptional transactivation by heterodimerization with bHLH proteins (Pagliuca et al., 1995).

Molekulargewicht: 17 kDa

Gen-ID: 3400

NCBI Accession: NP_001537

UniProt: P47928