This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This ID4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human ID4.
Idb4 antikoerper, bHLHb27 antikoerper, cb547 antikoerper, fb77d04 antikoerper, sb:cb547 antikoerper, wu:fb77d04 antikoerper, zgc:123214 antikoerper, bhlhb27 antikoerper, id4 antikoerper, id4a antikoerper, idb4 antikoerper, IDB4 antikoerper, inhibitor of DNA binding 4 antikoerper, inhibitor of DNA binding 4, HLH protein antikoerper, inhibitor of DNA binding 4, HLH protein S homeolog antikoerper, Id4 antikoerper, id4 antikoerper, id4.S antikoerper, ID4 antikoerper
Hintergrund
ID4 is transcription factors containing a basic helix-loop-helix (bHLH) motif regulate expression of tissue-specific genes in a number of mammalian and insect systems. DNA-binding activity of the bHLH proteins is dependent on formation of homo- and/or heterodimers. Dominant-negative HLH proteins encoded by Id-related genes, such as ID4, also contain the HLH-dimerization domain but lack the DNA-binding basic domain. Consequently, Id proteins inhibit binding to DNA and transcriptional transactivation by heterodimerization with bHLH proteins