MCM8 Antikörper

Produktnummer ABIN2461402

Produktdetails anti-MCM8 Antikörper

Target: MCM8 (Minichromosome Maintenance Deficient 8 (MCM8))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MCM8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MCM8.

Anwendungsinformationen

Applikationshinweise: MCM8 antibody can be used for detection of MCM8 by ELISA at 1:62500. MCM8 antibody can be used for detection of MCM8 by western blot at 0.125 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store MCM8 antibody at -20 °C.

Details zu MCM8

Target: MCM8 (Minichromosome Maintenance Deficient 8 (MCM8))

Andere Bezeichnung: MCM8 (MCM8 Produkte)

Synonyme: C20orf154 antikoerper, dJ967N21.5 antikoerper, 5730432L01Rik antikoerper, minichromosome maintenance 8 homologous recombination repair factor antikoerper, minichromosome maintenance 8 homologous recombination repair factor L homeolog antikoerper, MCM8 antikoerper, Mcm8 antikoerper, mcm8.L antikoerper

Hintergrund: MCM8 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein contains the central domain that is conserved among the MCM proteins. This protein has been shown to co-immunoprecipitate with MCM4, 6 and 7, which suggests that it may interact with other MCM proteins and play a role in DNA replication. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Molekulargewicht: 92 kDa, 92 kDa

Gen-ID: 84515

NCBI Accession: NP_115874

UniProt: Q9UJA3

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA