Annexin VII Antikörper

Produktnummer ABIN2461376

Produktdetails anti-Annexin VII Antikörper

Target: Annexin VII (ANXA7) (Annexin A7 (ANXA7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Annexin VII Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ANXA7.

Anwendungsinformationen

Applikationshinweise: ANXA7 antibody can be used for detection of ANXA7 by ELISA at 1:312500. ANXA7 antibody can be used for detection of ANXA7 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store ANXA7 antibody at -20 °C.

Details zu Annexin VII

Target: Annexin VII (ANXA7) (Annexin A7 (ANXA7))

Andere Bezeichnung: ANXA7 (ANXA7 Produkte)

Synonyme: ANX7 antikoerper, SNX antikoerper, SYNEXIN antikoerper, AI265384 antikoerper, AI316497 antikoerper, Anx7 antikoerper, synexin antikoerper, anxa7 antikoerper, MGC76267 antikoerper, MGC82023 antikoerper, ANXA7 antikoerper, MGC83033 antikoerper, annexin A7 antikoerper, annexin VII antikoerper, annexin A7 S homeolog antikoerper, ANXA7 antikoerper, Anxa7 antikoerper, anxa7 antikoerper, anxa7.S antikoerper, PTRG_02166 antikoerper, BRAFLDRAFT_231082 antikoerper, PAAG_00136 antikoerper, MCYG_04180 antikoerper, VDBG_06328 antikoerper, MGYG_02426 antikoerper

Hintergrund: ANXA7 is a member of the annexin family of calcium-dependent phospholipid binding proteins. The Annexin VII gene contains 14 exons and spans approximately 34 kb of DNA. An alternatively spliced cassette exon results in two mRNA transcripts of 2.0 and 2.4 kb which are predicted to generate two protein isoforms differing in their N-terminal domain. The alternative splicing event is tissue specific and the mRNA containing the cassette exon is prevalent in brain, heart and skeletal muscle. The transcripts also differ in their 3'-non coding regions by the use of two alternative poly (A) signals. The selection of poly (A) signals is independent of the mRNA splicing pattern. Annexin VII encodes a protein with a molecular weight of approximately 51 kDa with a unique, highly hydrophobic N-terminal domain of 167 amino acids and a conserved C-terminal region of 299 amino acids. The latter domain is composed of alternating hydrophobic and hydrophilic segments. Structural analysis of the protein suggests that Annexin VII is a membrane binding protein with diverse properties including voltage-sensitive calcium channel activity, ion selectivity and membrane fusion.

Molekulargewicht: 51 kDa, 53 kDa

Gen-ID: 310

NCBI Accession: NP_001147

UniProt: Q5T0M6