DREAM Antikörper

Produktnummer ABIN2460323

Produktdetails anti-DREAM Antikörper

Target: DREAM (KCNIP3) (Kv Channel Interacting Protein 3, Calsenilin (KCNIP3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DREAM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CSEN.

Anwendungsinformationen

Applikationshinweise: CSEN antibody can be used for detection of CSEN by ELISA at 1:12500. CSEN antibody can be used for detection of CSEN by western blot at 2.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CSEN antibody at -20 °C.

Details zu DREAM

Target: DREAM (KCNIP3) (Kv Channel Interacting Protein 3, Calsenilin (KCNIP3))

Andere Bezeichnung: CSEN (KCNIP3 Produkte)

Synonyme: CSEN antikoerper, DREAM antikoerper, KCHIP3 antikoerper, 4933407H12Rik antikoerper, AI413860 antikoerper, Csen antikoerper, KChIP3 antikoerper, R74849 antikoerper, Dream antikoerper, rKChIP3 antikoerper, csen antikoerper, im:7145308 antikoerper, kcnip3 antikoerper, zgc:73306 antikoerper, KCNIP3 antikoerper, potassium voltage-gated channel interacting protein 3 antikoerper, Kv channel-interacting protein 4 antikoerper, calsenilin antikoerper, Kv channel interacting protein 3, calsenilin antikoerper, Kv channel interacting protein 3b, calsenilin antikoerper, KCNIP3 antikoerper, LOC5568664 antikoerper, CpipJ_CPIJ002549 antikoerper, Tsp_05009 antikoerper, Kcnip3 antikoerper, kcnip3b antikoerper, kcnip3 antikoerper

Hintergrund: CSEN is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The protein encoded by this gene is also shown to function as a calcium-regulated transcriptional repressor, and to interact with presenilins. Mutations in the presenilin genes have been implicated in Alzheimer's disease.

Molekulargewicht: 29 kDa

Gen-ID: 30818

NCBI Accession: NP_038462

UniProt: Q9Y2W7