ATP6V1C1 Antikörper

Produktnummer ABIN2460074

Produktdetails anti-ATP6V1C1 Antikörper

Target: ATP6V1C1 (ATPase, H+ Transporting, Lysosomal 42kDa, V1 Subunit C1 (ATP6V1C1))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATP6V1C1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ATP6V1C1.

Anwendungsinformationen

Applikationshinweise: ATP6V1C1 antibody can be used for detection of ATP6V1C1 by ELISA at 1:312500. ATP6V1C1 antibody can be used for detection of ATP6V1C1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store ATP6V1C1 antibody at -20 °C.

Details zu ATP6V1C1

Target: ATP6V1C1 (ATPase, H+ Transporting, Lysosomal 42kDa, V1 Subunit C1 (ATP6V1C1))

Andere Bezeichnung: ATP6V1C1 (ATP6V1C1 Produkte)

Synonyme: ATP6C antikoerper, ATP6D antikoerper, VATC antikoerper, Vma5 antikoerper, 1700025B18Rik antikoerper, U13839 antikoerper, vatC antikoerper, ATPase antikoerper, atp6v1c1 antikoerper, si:zc215i13.2 antikoerper, wu:fd12h05 antikoerper, atp6v1c1l antikoerper, zgc:92684 antikoerper, ATPase H+ transporting V1 subunit C1 antikoerper, ATPase, H+ transporting, lysosomal V1 subunit C1 antikoerper, ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 antikoerper, ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 L homeolog antikoerper, ATPase, H+ transporting, lysosomal, V1 subunit C1a antikoerper, ATPase, H+ transporting, lysosomal, V1 subunit C1b antikoerper, ATP6V1C1 antikoerper, Atp6v1c1 antikoerper, atp6v1c1 antikoerper, atp6v1c1.L antikoerper, atp6v1c1a antikoerper, atp6v1c1b antikoerper

Hintergrund: ATP6V1C1 is a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene is one of two genes that encode the V1 domain C subunit proteins and is found ubiquitously. This C subunit is analogous but not homologous to gamma subunit of F-ATPases. Previously, this gene was designated ATP6D.This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene is one of two genes that encode the V1 domain C subunit proteins and is found ubiquitously. This C subunit is analogous but not homologous to gamma subunit of F-ATPases. Previously, this gene was designated ATP6D. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Molekulargewicht: 42 kDa

Gen-ID: 528

NCBI Accession: NP_001686

UniProt: P21283

Pathways: Transition Metal Ion Homeostasis, Proton Transport