ATP6V1C1 Antikörper

Produktnummer ABIN7247105

Produktdetails anti-ATP6V1C1 Antikörper

Target: ATP6V1C1 (ATPase, H+ Transporting, Lysosomal 42kDa, V1 Subunit C1 (ATP6V1C1))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATP6V1C1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Antigen affinity purification

Immunogen: Fusion protein of human ATP6V1C1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:100-1:200, ELISA 1:5000-1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.6 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ATP6V1C1

Target: ATP6V1C1 (ATPase, H+ Transporting, Lysosomal 42kDa, V1 Subunit C1 (ATP6V1C1))

Andere Bezeichnung: ATP6V1C1 (ATP6V1C1 Produkte)

Synonyme: ATP6C antikoerper, ATP6D antikoerper, VATC antikoerper, Vma5 antikoerper, 1700025B18Rik antikoerper, U13839 antikoerper, vatC antikoerper, ATPase antikoerper, atp6v1c1 antikoerper, si:zc215i13.2 antikoerper, wu:fd12h05 antikoerper, atp6v1c1l antikoerper, zgc:92684 antikoerper, ATPase H+ transporting V1 subunit C1 antikoerper, ATPase, H+ transporting, lysosomal V1 subunit C1 antikoerper, ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 antikoerper, ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 L homeolog antikoerper, ATPase, H+ transporting, lysosomal, V1 subunit C1a antikoerper, ATPase, H+ transporting, lysosomal, V1 subunit C1b antikoerper, ATP6V1C1 antikoerper, Atp6v1c1 antikoerper, atp6v1c1 antikoerper, atp6v1c1.L antikoerper, atp6v1c1a antikoerper, atp6v1c1b antikoerper

Hintergrund: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene is one of two genes that encode the V1 domain C subunit proteins and is found ubiquitously. This C subunit is analogous but not homologous to gamma subunit of F-ATPases. Previously, this gene was designated ATP6D.

Molekulargewicht:

Observed_MW: Refer to figures

Calculated_MW: 44 kDa

UniProt: P21283

Pathways: Transition Metal Ion Homeostasis, Proton Transport