COL1A2 Antikörper

Produktnummer ABIN2460049

Produktdetails anti-COL1A2 Antikörper

Target: COL1A2 (Collagen, Type I, alpha 2 (COL1A2))

Reaktivität: Human, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COL1A2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human COL1A2.

Anwendungsinformationen

Applikationshinweise: COL1A2 antibody can be used for detection of COL1A2 by ELISA at 1:62500. COL1A2 antibody can be used for detection of COL1A2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store COL1A2 antibody at -20 °C.

Details zu COL1A2

Target: COL1A2 (Collagen, Type I, alpha 2 (COL1A2))

Andere Bezeichnung: COL1A2 (COL1A2 Produkte)

Synonyme: AA960264 antikoerper, AI325291 antikoerper, Col1a-2 antikoerper, Cola-2 antikoerper, Cola2 antikoerper, oim antikoerper, OI4 antikoerper, Gas-6 antikoerper, alpha2(I) antikoerper, hm:zehn2357 antikoerper, wu:fa98d05 antikoerper, wu:fa99g10 antikoerper, wu:fb04c08 antikoerper, wu:fb11d06 antikoerper, zehn2357 antikoerper, coagulation factor II, thrombin antikoerper, collagen, type I, alpha 2 antikoerper, collagen type I alpha 2 chain antikoerper, collagen type I alpha 2 L homeolog antikoerper, growth arrest specific 6 antikoerper, F2 antikoerper, Col1a2 antikoerper, col1a2.L antikoerper, COL1A2 antikoerper, Gas6 antikoerper, col1a2 antikoerper

Hintergrund: COL1A2 is the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity.This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Molekulargewicht: 150 kDa

Gen-ID: 1278

NCBI Accession: NP_000080

UniProt: P08123