COL1A2 Antikörper (C-Term)

Produktnummer ABIN2855530

Produktdetails anti-COL1A2 Antikörper

Target: COL1A2 (Collagen, Type I, alpha 2 (COL1A2))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COL1A2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Kreuzreaktivität: Human, Maus, Zebrafisch (Danio rerio)

Produktmerkmale: Rabbit Polyclonal antibody to COL1A2 (collagen, type I, alpha 2)
COL1A2 antibody [C2C3], C-term

Aufreinigung: Purified by antigen-affinity chromatography.

Güteklasse: KO Validated

Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human COL1A2. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Validation: KO/KD, Orthogonal, Overexpression

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 2.61 mg/mL

Buffer: 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu COL1A2

Target: COL1A2 (Collagen, Type I, alpha 2 (COL1A2))

Andere Bezeichnung: collagen type I alpha 2 chain (COL1A2 Produkte)

Synonyme: AA960264 antikoerper, AI325291 antikoerper, Col1a-2 antikoerper, Cola-2 antikoerper, Cola2 antikoerper, oim antikoerper, OI4 antikoerper, Gas-6 antikoerper, alpha2(I) antikoerper, hm:zehn2357 antikoerper, wu:fa98d05 antikoerper, wu:fa99g10 antikoerper, wu:fb04c08 antikoerper, wu:fb11d06 antikoerper, zehn2357 antikoerper, coagulation factor II, thrombin antikoerper, collagen, type I, alpha 2 antikoerper, collagen type I alpha 2 chain antikoerper, collagen type I alpha 2 L homeolog antikoerper, growth arrest specific 6 antikoerper, F2 antikoerper, Col1a2 antikoerper, col1a2.L antikoerper, COL1A2 antikoerper, Gas6 antikoerper, col1a2 antikoerper

Hintergrund: This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish]

Cellular Localization: Secreted , extracellular space , extracellular matrix

Molekulargewicht: 129 kDa

Gen-ID: 1278

UniProt: P08123