DAAM1 Antikörper

Produktnummer ABIN2459853

Produktdetails anti-DAAM1 Antikörper

Target: DAAM1 (Dishevelled Associated Activator of Morphogenesis 1 (DAAM1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DAAM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DAAM1.

Anwendungsinformationen

Applikationshinweise: DAAM1 antibody can be used for detection of DAAM1 by ELISA at 1:62500. DAAM1 antibody can be used for detection of DAAM1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store DAAM1 antibody at -20 °C.

Details zu DAAM1

Target: DAAM1 (Dishevelled Associated Activator of Morphogenesis 1 (DAAM1))

Andere Bezeichnung: DAAM1 (DAAM1 Produkte)

Synonyme: 1700066F09Rik antikoerper, 2310028E21Rik antikoerper, AI503486 antikoerper, E130308H01 antikoerper, mKIAA0666 antikoerper, daam-1 antikoerper, xdaam1 antikoerper, daam1 antikoerper, DAAM1 antikoerper, DKFZp468D0524 antikoerper, daam1l antikoerper, fc83b10 antikoerper, si:ch211-87i20.1 antikoerper, wu:fc83b10 antikoerper, dishevelled associated activator of morphogenesis 1 antikoerper, dishevelled associated activator of morphogenesis 1 S homeolog antikoerper, dishevelled associated activator of morphogenesis 1a antikoerper, dishevelled associated activator of morphogenesis 1b antikoerper, DAAM1 antikoerper, Daam1 antikoerper, daam1.S antikoerper, daam1a antikoerper, daam1 antikoerper, daam1b antikoerper

Hintergrund: Functions of the cell cortex, including motility, adhesion, and cytokinesis, are mediated by the reorganization of the actin cytoskeleton and recent evidence suggests a role for the Formin homology (FH) proteins in these processes. The protein encoded by this gene contains FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. Wnt/Fz signaling activates the small GTPase Rho, a key regulator of cytoskeleton architecture, to control cell polarity and movement during development. Activation requires Dvl-Rho complex formation, an assembly mediated by this gene product, which is thought to function as a scaffolding protein.Functions of the cell cortex, including motility, adhesion, and cytokinesis, are mediated by the reorganization of the actin cytoskeleton and recent evidence suggests a role for the Formin homology (FH) proteins in these processes. The protein encoded by this gene contains FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. Wnt/Fz signaling activates the small GTPase Rho, a key regulator of cytoskeleton architecture, to control cell polarity and movement during development. Activation requires Dvl-Rho complex formation, an assembly mediated by this gene product, which is thought to function as a scaffolding protein. Evidence of alternative splicing has been observed for this gene but the full-length nature of these variants has not been determined.

Molekulargewicht: 123 kDa

Gen-ID: 23002

NCBI Accession: NP_055807

UniProt: Q9Y4D1

Pathways: WNT Signalweg