CYP11A1 Antikörper

Produktnummer ABIN2459507

Produktdetails anti-CYP11A1 Antikörper

Target: CYP11A1 (Cytochrome P450, Family 11, Subfamily A, Polypeptide 1 (CYP11A1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYP11A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CYP11A1.

Anwendungsinformationen

Applikationshinweise: CYP11A1 antibody can be used for detection of CYP11A1 by ELISA at 1:1562500. CYP11A1 antibody can be used for detection of CYP11A1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CYP11A1 antibody at -20 °C.

Details zu CYP11A1

Target: CYP11A1 (Cytochrome P450, Family 11, Subfamily A, Polypeptide 1 (CYP11A1))

Andere Bezeichnung: CYP11A1 (CYP11A1 Produkte)

Synonyme: CYP11A antikoerper, CYP11A1 antikoerper, CYPXIA1 antikoerper, P450SCC antikoerper, Cyp11a antikoerper, Cypxia1 antikoerper, D9Ertd411e antikoerper, P450scc antikoerper, Scc antikoerper, cscc antikoerper, P450(scc) antikoerper, SSC antikoerper, cytochrome P450 family 11 subfamily A member 1 antikoerper, cholesterol side-chain cleavage enzyme, mitochondrial-like antikoerper, cytochrome P450 cholesterol side-chain cleavage antikoerper, cytochrome P450, family 11, subfamily a, polypeptide 1 antikoerper, cytochrome P450, family 11, subfamily A, polypeptide 1 antikoerper, CYP11A1 antikoerper, LOC101827747 antikoerper, Cyp11a1 antikoerper

Hintergrund: CYP11A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. CYP11A1 localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide.

Molekulargewicht: 57 kDa

Gen-ID: 1583

NCBI Accession: NP_000772

UniProt: P05108

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process, Cellular Response to Molecule of Bacterial Origin