SIN3B Antikörper

Produktnummer ABIN2459432

Produktdetails anti-SIN3B Antikörper

Target: SIN3B (SIN3 Transcription Regulator Homolog B (SIN3B))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SIN3B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SIN3B.

Anwendungsinformationen

Applikationshinweise: SIN3B antibody can be used for detection of SIN3B by ELISA at 1:312500. SIN3B antibody can be used for detection of SIN3B by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store SIN3B antibody at -20 °C.

Details zu SIN3B

Target: SIN3B (SIN3 Transcription Regulator Homolog B (SIN3B))

Andere Bezeichnung: SIN3B (SIN3B Produkte)

Synonyme: fj63d08 antikoerper, si:dkey-6n6.6 antikoerper, wu:fj63d08 antikoerper, 2810430C10Rik antikoerper, SIN3 transcription regulator family member B antikoerper, SIN3 transcription regulator family member B S homeolog antikoerper, transcriptional regulator, SIN3B (yeast) antikoerper, sin3b antikoerper, SIN3B antikoerper, sin3b.S antikoerper, Sin3b antikoerper

Hintergrund: SIN3B acts as a transcriptional repressor. It interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities.It also interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. SIN3B also forms a complex with FOXK1 which represses transcription.

Molekulargewicht: 133 kDa

Gen-ID: 23309

NCBI Accession: NP_056075

UniProt: O75182