Selenoprotein S Antikörper

Produktnummer ABIN2459165

Produktdetails anti-Selenoprotein S Antikörper

Target: Selenoprotein S (SELS)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Selenoprotein S Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SELS.

Anwendungsinformationen

Applikationshinweise: SELS antibody can be used for detection of SELS by ELISA at 1:312500. SELS antibody can be used for detection of SELS by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store SELS antibody at -20 °C.

Details zu Selenoprotein S

Target: Selenoprotein S (SELS)

Andere Bezeichnung: SELS (SELS Produkte)

Synonyme: ADO15 antikoerper, SBBI8 antikoerper, SELS antikoerper, SEPS1 antikoerper, 1500011E07Rik antikoerper, C78786 antikoerper, H-4 antikoerper, H-47 antikoerper, H4 antikoerper, H47 antikoerper, Sels antikoerper, sg2 antikoerper, selenoprotein S antikoerper, SELENOS antikoerper, Selenos antikoerper

Hintergrund: SELS is a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Studies suggest that this protein may regulate cytokine production, and thus play a key role in the control of the inflammatory response.This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Studies suggest that this protein may regulate cytokine production, and thus play a key role in the control of the inflammatory response. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.

Molekulargewicht: 21 kDa

Gen-ID: 55829

NCBI Accession: NP_060915

UniProt: Q9BQE4

Pathways: Cellular Response to Molecule of Bacterial Origin, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Cell RedoxHomeostasis, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interaktom