RFC4 Antikörper

Produktnummer ABIN2458986

Produktdetails anti-RFC4 Antikörper

Target: RFC4 (Replication Factor C (Activator 1) 4, 37kDa (RFC4))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RFC4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RFC4.

Anwendungsinformationen

Applikationshinweise: RFC4 antibody can be used for detection of RFC4 by ELISA at 1:62500. RFC4 antibody can be used for detection of RFC4 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store RFC4 antibody at -20 °C.

Details zu RFC4

Target: RFC4 (Replication Factor C (Activator 1) 4, 37kDa (RFC4))

Andere Bezeichnung: RFC4 (RFC4 Produkte)

Synonyme: 44.t00003 antikoerper, 21.m03053 antikoerper, rfc4 antikoerper, A1 antikoerper, AI894123 antikoerper, AU040575 antikoerper, RFC37 antikoerper, rfc2 antikoerper, replication factor C subunit 4 antikoerper, Replication factor C subunit 4 antikoerper, replication factor C (activator 1) 4 antikoerper, replication factor C subunit 4 L homeolog antikoerper, PFL2005w antikoerper, EHI_167150 antikoerper, TP03_0432 antikoerper, Tb11.01.1310 antikoerper, BBOV_IV002210 antikoerper, rfc4 antikoerper, rfc-4 antikoerper, Rfc4 antikoerper, RFC4 antikoerper, rfc4.L antikoerper

Hintergrund: The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. This subunit may be involved in the elongation of the multiprimed DNA template.The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 37 kD subunit. This subunit forms a core complex with the 36 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcript variants encoding the same protein have been reported.

Molekulargewicht: 40 kDa

Gen-ID: 5984

NCBI Accession: NP_002907

UniProt: P35249

Pathways: Telomere Maintenance, DNA Reparatur, DNA Replication, Synthesis of DNA