ATP2B3 Antikörper

Produktnummer ABIN2458839

Produktdetails anti-ATP2B3 Antikörper

Target: ATP2B3 (ATPase, Ca++ Transporting, Plasma Membrane 3 (ATP2B3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATP2B3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ATP2B3.

Anwendungsinformationen

Applikationshinweise: ATP2B3 antibody can be used for detection of ATP2B3 by ELISA at 1:312500. ATP2B3 antibody can be used for detection of ATP2B3 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store ATP2B3 antibody at -20 °C.

Details zu ATP2B3

Target: ATP2B3 (ATPase, Ca++ Transporting, Plasma Membrane 3 (ATP2B3))

Andere Bezeichnung: ATP2B3 (ATP2B3 Produkte)

Synonyme: PMCA3 antikoerper, PMCA3a antikoerper, SCAX1 antikoerper, atp2b3 antikoerper, pmca3a antikoerper, zgc:92885 antikoerper, 6430519O13Rik antikoerper, Pmca3 antikoerper, ATPase plasma membrane Ca2+ transporting 3 antikoerper, ATPase, Ca++ transporting, plasma membrane 3a antikoerper, ATPase, Ca++ transporting, plasma membrane 3 antikoerper, plasma membrane calcium-transporting ATPase 2 antikoerper, ATP2B3 antikoerper, atp2b3a antikoerper, Atp2b3 antikoerper, atp2b3 antikoerper, LOC100639471 antikoerper

Hintergrund: ATP2B3 gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. ATP2B3 is the plasma membrane calcium ATPase isoform 3.The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 3. Alternatively spliced transcript variants encoding different isoforms have been identified.

Molekulargewicht: 134 kDa

Gen-ID: 492

NCBI Accession: NP_001001344

UniProt: Q16720

Pathways: Ribonucleoside Biosynthetic Process