CPB2 Antikörper

Produktnummer ABIN2458761

Produktdetails anti-CPB2 Antikörper

Target: CPB2 (Carboxypeptidase B2 (Plasma) (CPB2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CPB2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CPB2.

Anwendungsinformationen

Applikationshinweise: CPB2 antibody can be used for detection of CPB2 by ELISA at 1:1562500. CPB2 antibody can be used for detection of CPB2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CPB2 antibody at -20 °C.

Details zu CPB2

Target: CPB2 (Carboxypeptidase B2 (Plasma) (CPB2))

Andere Bezeichnung: CPB2 (CPB2 Produkte)

Synonyme: CPU antikoerper, PCPB antikoerper, TAFI antikoerper, 1110032P04Rik antikoerper, 4930405E17Rik antikoerper, AI255929 antikoerper, CPR antikoerper, Cpu antikoerper, pCPB antikoerper, zgc:112493 antikoerper, carboxypeptidase B2 antikoerper, carboxypeptidase B2 (plasma) antikoerper, CPB2 antikoerper, Cpb2 antikoerper, cpb2 antikoerper

Hintergrund: Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). CPB2 is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). The protein encoded by this gene is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for this gene and its promoter region. Available sequence data analyses indicate splice variants that encode different isoforms.

Molekulargewicht: 36 kDa

Gen-ID: 1361

NCBI Accession: NP_001863

UniProt: Q96IY4

Pathways: Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis