CPB2 Antikörper (AA 119-148)

Produktnummer ABIN390451

Produktdetails anti-CPB2 Antikörper

Target: CPB2 (Carboxypeptidase B2 (Plasma) (CPB2))

Bindungsspezifität: AA 119-148

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CPB2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This CPB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 119-148 amino acids from the Central region of human CPB2.

Klon: RB19013

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu CPB2

Target: CPB2 (Carboxypeptidase B2 (Plasma) (CPB2))

Andere Bezeichnung: CPB2 (CPB2 Produkte)

Synonyme: CPU antikoerper, PCPB antikoerper, TAFI antikoerper, 1110032P04Rik antikoerper, 4930405E17Rik antikoerper, AI255929 antikoerper, CPR antikoerper, Cpu antikoerper, pCPB antikoerper, zgc:112493 antikoerper, carboxypeptidase B2 antikoerper, carboxypeptidase B2 (plasma) antikoerper, CPB2 antikoerper, Cpb2 antikoerper, cpb2 antikoerper

Hintergrund: Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). CPB2 is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for its gene and its promoter region.

Molekulargewicht: 48424

Gen-ID: 1361

NCBI Accession: NP_001265470, NP_001863

UniProt: Q96IY4

Pathways: Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis