KDM6A Antikörper

Produktnummer ABIN2458408

Produktdetails anti-KDM6A Antikörper

Target: KDM6A (Lysine (K)-Specific Demethylase 6A (KDM6A))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KDM6A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human UTX.

Anwendungsinformationen

Applikationshinweise: UTX antibody can be used for detection of UTX by ELISA at 1:312500. UTX antibody can be used for detection of UTX by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store UTX antibody at -20 °C.

Details zu KDM6A

Target: KDM6A (Lysine (K)-Specific Demethylase 6A (KDM6A))

Andere Bezeichnung: UTX (KDM6A Produkte)

Synonyme: KABUK2 antikoerper, UTX antikoerper, bA386N14.2 antikoerper, Utx antikoerper, si:ch211-222m21.1 antikoerper, utx antikoerper, kdm6a antikoerper, tutx antikoerper, uty antikoerper, xtutx antikoerper, lysine demethylase 6A antikoerper, lysine-specific demethylase 6A antikoerper, lysine (K)-specific demethylase 6A antikoerper, lysine demethylase 6A S homeolog antikoerper, KDM6A antikoerper, LOC100539898 antikoerper, Kdm6a antikoerper, kdm6a antikoerper, kdm6a.S antikoerper

Hintergrund: UTX is a histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. It demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-27'. UTX plays a central role in regulation of posterior development, by regulating HOX gene expression. Demethylation of 'Lys-27' of histone H3 is concomitent with methylation of 'Lys-4' of histone H3, and regulates the recruitment of the PRC1 complex and monoubiquitination of histone H2A.

Molekulargewicht: 154 kDa

Gen-ID: 7403

NCBI Accession: NP_066963

UniProt: O15550

Pathways: Tube Formation, Warburg Effekt