KCNJ1 Antikörper

Produktnummer ABIN2458147

Produktdetails anti-KCNJ1 Antikörper

Target: KCNJ1 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KCNJ1 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human KCNJ1.

Anwendungsinformationen

Applikationshinweise: KCNJ1 antibody can be used for detection of KCNJ1 by ELISA at 1:312500. KCNJ1 antibody can be used for detection of KCNJ1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store KCNJ1 antibody at -20 °C.

Details zu KCNJ1

Target: KCNJ1 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1))

Andere Bezeichnung: KCNJ1 (KCNJ1 Produkte)

Synonyme: KIR1.1 antikoerper, ROMK antikoerper, ROMK1 antikoerper, kir1.1 antikoerper, romk1 antikoerper, Kcnj antikoerper, Kir1.1 antikoerper, Romk2 antikoerper, kcnj1 antikoerper, wu:fl37c05 antikoerper, zgc:63534 antikoerper, potassium voltage-gated channel subfamily J member 1 antikoerper, potassium voltage-gated channel subfamily J member 1 L homeolog antikoerper, potassium inwardly-rectifying channel, subfamily J, member 1 antikoerper, potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 1 antikoerper, KCNJ1 antikoerper, kcnj1.L antikoerper, kcnj1 antikoerper, Kcnj1 antikoerper, kcnj1a.1 antikoerper

Hintergrund: KCNJ1 has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for KCNJ1.Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis.Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 45 kDa

Gen-ID: 3758

NCBI Accession: NP_000211

UniProt: P48048