KIF2A Antikörper

Produktnummer ABIN2458064

Produktdetails anti-KIF2A Antikörper

Target: KIF2A (Kinesin Heavy Chain Member 2A (KIF2A))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KIF2A Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human KIF2A.

Anwendungsinformationen

Applikationshinweise: KIF2A antibody can be used for detection of KIF2A by ELISA at 1:62500. KIF2A antibody can be used for detection of KIF2A by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store KIF2A antibody at -20 °C.

Details zu KIF2A

Target: KIF2A (Kinesin Heavy Chain Member 2A (KIF2A))

Andere Bezeichnung: KIF2A (KIF2A Produkte)

Synonyme: HK2 antikoerper, KIF2 antikoerper, C530030B14Rik antikoerper, Kif2 antikoerper, Kns2 antikoerper, M-kinesin antikoerper, kif2-a antikoerper, fj55b02 antikoerper, wu:fj55b02 antikoerper, kinesin family member 2A antikoerper, kinesin heavy chain member 2A L homeolog antikoerper, kinesin heavy chain member 2A antikoerper, zgc:103670 antikoerper, Kinesin-2 antikoerper, KIF2A antikoerper, Kif2a antikoerper, kif2a.L antikoerper, zgc:103670 antikoerper, GL50803_17333 antikoerper, GL50803_16456 antikoerper

Hintergrund: KIF2A belongs to the kinesin-like protein family, MCAK/KIF2 subfamily. It contains 1 kinesin-motor domain. KIF2A plus end-directed microtubule-dependent motor required for normal brain development. It may regulate microtubule dynamics during axonal growth. KIF2A is implicated in formation of bipolar mitotic spindles. It has microtubule depolymerization activity. Hela cells lacking KIF2A show asymmetric or monopolar mitotic spindles. Osteosarcoma cells (U2OS) lacking KIF2A or KIF2B show disorganised or monopolar mitotic spindles.Kinesins, such as KIF2, are microtubule-associated motor proteins. For background information on kinesins, see MIM 148760.

Molekulargewicht: 80 kDa

Gen-ID: 3796

NCBI Accession: NP_004511

UniProt: O00139

Pathways: Microtubule Dynamics, Ribonucleoprotein Complex Subunit Organization