Sp3 Antikörper

Produktnummer ABIN2458017

Produktdetails anti-Sp3 Antikörper

Target: Sp3 (Sp3 Transcription Factor (Sp3))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Sp3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SP3.

Anwendungsinformationen

Applikationshinweise: SP3 antibody can be used for detection of SP3 by ELISA at 1:312500. SP3 antibody can be used for detection of SP3 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store SP3 antibody at -20 °C.

Details zu Sp3

Target: Sp3 (Sp3 Transcription Factor (Sp3))

Andere Bezeichnung: SP3 (Sp3 Produkte)

Synonyme: SPR2 antikoerper, D130027J01Rik antikoerper, SP3 antikoerper, sp3 antikoerper, zgc:162922 antikoerper, Sp3 transcription factor antikoerper, trans-acting transcription factor 3 antikoerper, sp3a transcription factor antikoerper, Sp3 transcription factor S homeolog antikoerper, SP3 antikoerper, Sp3 antikoerper, sp3a antikoerper, sp3.S antikoerper

Hintergrund: SP3 is a transcriptional factor that can act as an activator or repressor, probably in a isoform-specific manner. SP3 binds to GT and GC boxes promoters elements.This gene belongs to a family of Sp1 related genes that encode transcription factors that regulate transcription by binding to consensus GC- and GT-box regulatory elements in target genes. This protein contains a zinc finger DNA-binding domain and several transactivation domains, and has been reported to function as a bifunctional transcription factor that either stimulates or represses the transcription of numerous genes. Transcript variants encoding different isoforms have been described for this gene, and one has been reported to initiate translation from a non-AUG (AUA) start codon. Additional isoforms, resulting from the use of alternate downstream translation initiation sites, have also been noted.

Molekulargewicht: 82 kDa

Gen-ID: 6670

NCBI Accession: NP_003102

UniProt: Q02447