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ARID1A Antikörper (N-Term)
ARID1A
Reaktivität: Human, Maus, Ratte
ELISA, WB
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN2457886
Produktdetails anti-ARID1A Antikörper
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Target
Alle ARID1A Antikörper anzeigen
ARID1A
(AT Rich Interactive Domain 1A (SWI-Like) (ARID1A))
Bindungsspezifität
Alle Epitope für ARID1A Antikörper
N-Term
Reaktivität
Alle Reaktivitäten für ARID1A Antikörper
Human, Maus, Ratte
Wirt
Alle Wirte für ARID1A Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für ARID1A Antikörper
Polyklonal
Konjugat
Alle Konjugate für ARID1A Antikörper
Dieser ARID1A Antikörper ist unkonjugiert
Applikation
Alle Applikationen für ARID1A Antikörper
ELISA, Western Blotting (WB)
Spezifität
ARID1A antibody is human, mouse and rat reactive. Multiple isoforms of ARID1A protein are known to exist.
Aufreinigung
ARID1A antibody is affinity chromatography purified via peptide column.
Immunogen
ARID1A antibody was raised against an 18 amino acid peptide near the amino terminus of human ARID1A.
Isotyp
IgG
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Discover our top product ARID1A Primärantikörper
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Anwendungsinformationen
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Applikationshinweise
ARID1A antibody can be used for detection of ARID1A by Western blot at 1 - 2 μg/mL.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
1 mg/mL
Buffer
PBS containing 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Can be stored at 4 °C for three months and -20 °C, stable for up to one year.
Details zu ARID1A
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Target
ARID1A
(AT Rich Interactive Domain 1A (SWI-Like) (ARID1A))
Andere Bezeichnung
ARID1A (ARID1A Produkte )
Synonyme
B120 antikoerper, BAF250 antikoerper, BAF250a antikoerper, BM029 antikoerper, C1orf4 antikoerper, ELD antikoerper, MRD14 antikoerper, OSA1 antikoerper, P270 antikoerper, SMARCF1 antikoerper, hELD antikoerper, hOSA1 antikoerper, 1110030E03Rik antikoerper, Osa1 antikoerper, Smarcf1 antikoerper, ARID1A antikoerper, wu:fb79b07 antikoerper, wu:fb95g08 antikoerper, zgc:171438 antikoerper, AT-rich interaction domain 1A antikoerper, AT rich interactive domain 1A (SWI-like) antikoerper, AT rich interactive domain 1Aa (SWI-like) antikoerper, ARID1A antikoerper, Arid1a antikoerper, arid1a antikoerper, arid1aa antikoerper
Hintergrund
The ARID1A protein is a member of the SWI/SNF family, whose members are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. ARID1A is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin (1). It possesses a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. The C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation. It is thought that ARID1A confers specificity to the SNF/SWI complex and may recruit the complex to its targets through either protein-DNA or protein-protein interactions (2).
Molekulargewicht
Predicted: 133, 227, 251 kDa Observed: 130, 260 kDa
Gen-ID
8289
NCBI Accession
NP_006006
UniProt
O14497
Pathways
Intracellular Steroid Hormone Receptor Signaling Pathway , Tube Formation
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