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AVEN Antikörper

AVEN Reaktivität: Human, Maus WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2431089
  • Target Alle AVEN Antikörper anzeigen
    AVEN (Apoptosis, Caspase Activation Inhibitor (AVEN))
    Reaktivität
    • 48
    • 13
    • 6
    • 3
    Human, Maus
    Wirt
    • 46
    • 2
    Kaninchen
    Klonalität
    • 45
    • 2
    Polyklonal
    Konjugat
    • 17
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser AVEN Antikörper ist unkonjugiert
    Applikation
    • 41
    • 22
    • 13
    • 13
    • 7
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Aufreinigung
    Affinity purification
    Immunogen
    Synthetic peptide of human AVEN
    Isotyp
    IgG
    Top Product
    Discover our top product AVEN Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:25-1:100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.4 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    Konservierungsmittel
    Sodium azide
    Handhabung
    Avoid freeze / thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    AVEN (Apoptosis, Caspase Activation Inhibitor (AVEN))
    Andere Bezeichnung
    AVEN (AVEN Produkte)
    Synonyme
    AVEN antikoerper, pdcd12 antikoerper, aven antikoerper, wu:fc08c09 antikoerper, si:ch211-150c22.4 antikoerper, PDCD12 antikoerper, 1700013A01Rik antikoerper, 1700056A21Rik antikoerper, mAven-L antikoerper, mAven-S antikoerper, apoptosis and caspase activation inhibitor antikoerper, apoptosis, caspase activation inhibitor L homeolog antikoerper, apoptosis, caspase activation inhibitor antikoerper, Aven antikoerper, AVEN antikoerper, aven.L antikoerper, aven antikoerper
    Hintergrund
    AVEN, a cell death regulator, is an important signal inducer in acute leuke-mias. AVEN is a highly conserved peripheral membrane protein that protects the cell against the proteolytic activation of caspases as well as Apaf-1 mediated apoptosis by interfering with Apaf-1's ability to self-associate. Bcl-2 and Bad also interact with AVEN to prevent apoptosis. AVEN is highly expressed in ovary, heart, thymus, spleen, testis and colon, but can also be detected in other tissues. Erythropoietin and methylprednisolone may play important roles in the expression of AVEN in cardiac tissue, especially after a traumatic brain injury. In young patients suffering from acute lymphoblastic leukemia (ALL), AVEN expression may be a useful tool in prognosis prediction.
    Molekulargewicht
    Calculated MW: 39 kDa
    NCBI Accession
    NP_065104
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