Importin 4 Antikörper

Produktnummer ABIN2430313

Produktdetails anti-Importin 4 Antikörper

Target: Importin 4 (IPO4)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Importin 4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human IPO4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Konservierungsmittel: Sodium azide

Handhabung: Avoid freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Importin 4

Target: Importin 4 (IPO4)

Andere Bezeichnung: IPO4 (IPO4 Produkte)

Synonyme: Imp4 antikoerper, 8430408O15Rik antikoerper, AA409693 antikoerper, Imp4a antikoerper, RanBP4 antikoerper, importin 4 antikoerper, IPO4 antikoerper, Ipo4 antikoerper

Hintergrund: Importin-4is aproteinthat in humans is encoded by theIPO4gene. Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran.

Molekulargewicht: Calculated MW: 119 kDa

Pathways: Protein targeting to Nucleus