Importin 4 Antikörper (AA 350-400)

Produktnummer ABIN7453529

Produktdetails anti-Importin 4 Antikörper

Target: Importin 4 (IPO4)

Bindungsspezifität: AA 350-400

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Importin 4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Verwendungszweck: Rabbit anti-Importin 4 Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: between AA 350 and 400

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 5 - 15 μg/mg lysate

WB: Not recommended. ABIN7453529 has not performed satisfactorily when used for WB of Importin 4 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of Importin 4.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu Importin 4

Target: Importin 4 (IPO4)

Andere Bezeichnung: Importin 4 (IPO4 Produkte)

Synonyme: Imp4 antikoerper, 8430408O15Rik antikoerper, AA409693 antikoerper, Imp4a antikoerper, RanBP4 antikoerper, importin 4 antikoerper, IPO4 antikoerper, Ipo4 antikoerper

Hintergrund: Background: Importin 4 mediates the nuclear import of RPS3A. In vitro, it mediates the nuclear import of human cytomegalovirus UL84 by recognizing a non-classical NLS. Additionally, along with importin 7, importin 4 has been shown to be involved in nuclear import of HIF-1alpha [taken from the Universal Protein Resource (UniProt) ww.uniprot.org/uniprot/Q8TEX9].

Gen-ID: 79711

NCBI Accession: NP_078934

UniProt: Q8TEX9

Pathways: Protein targeting to Nucleus