MCM3 Antikörper

Produktnummer ABIN2428405

Produktdetails anti-MCM3 Antikörper

Target: MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MCM3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human MCM3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Konservierungsmittel: Sodium azide

Handhabung: Avoid freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu MCM3

Target: MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))

Andere Bezeichnung: MCM3 (MCM3 Produkte)

Synonyme: HCC5 antikoerper, P1-MCM3 antikoerper, P1.h antikoerper, RLFB antikoerper, AL033361 antikoerper, C80350 antikoerper, Mcmd antikoerper, P1 antikoerper, p1.m antikoerper, cb32 antikoerper, chunp6867 antikoerper, wu:fa26g03 antikoerper, CG4206 antikoerper, DmMCM3 antikoerper, DmMcm3 antikoerper, DmeMCM3 antikoerper, Dmel\\CG4206 antikoerper, MCM3 antikoerper, McM3 antikoerper, Mcp-PCR2 antikoerper, PCR2 antikoerper, dMCM3 antikoerper, xmcm3 antikoerper, minichromosome maintenance complex component 3 antikoerper, MCM3 minichromosome maintenance deficient 3 (S. cerevisiae) antikoerper, Minichromosome maintenance 3 antikoerper, minichromosome maintenance complex component 3 L homeolog antikoerper, MCM complex subunit Mcm3 antikoerper, MCM3 antikoerper, mcm3 antikoerper, Mcm3 antikoerper, mcm3.L antikoerper

Hintergrund: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly witHuman, MouseCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Two transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: Calculated MW: 91 kDa

Pathways: DNA Reparatur, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA