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NEDD4-2 Antikörper

NEDD4L Reaktivität: Human, Maus ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2423881
  • Target Alle NEDD4-2 (NEDD4L) Antikörper anzeigen
    NEDD4-2 (NEDD4L) (E3 ubiquitin-protein ligase NEDD4-like (NEDD4L))
    Reaktivität
    • 68
    • 44
    • 16
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 77
    • 4
    Kaninchen
    Klonalität
    • 70
    • 11
    Polyklonal
    Konjugat
    • 32
    • 7
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser NEDD4-2 Antikörper ist unkonjugiert
    Applikation
    • 38
    • 25
    • 13
    • 13
    • 8
    • 7
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant protein of human NEDD4L
    Isotyp
    IgG
    Top Product
    Discover our top product NEDD4L Primärantikörper
  • Applikationshinweise
    IHC 1:100-1:300
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.4 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    Konservierungsmittel
    Sodium azide
    Handhabung
    Avoid freeze / thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    NEDD4-2 (NEDD4L) (E3 ubiquitin-protein ligase NEDD4-like (NEDD4L))
    Andere Bezeichnung
    NEDD4L (NEDD4L Produkte)
    Synonyme
    NEDD4-2 antikoerper, NEDD4.2 antikoerper, RSP5 antikoerper, hNEDD4-2 antikoerper, nedd4 antikoerper, nedd4-2 antikoerper, NEDD4 antikoerper, Nedd4-2 antikoerper, 1300012C07Rik antikoerper, Nedd4b antikoerper, neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase antikoerper, NEDD4L antikoerper, neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase S homeolog antikoerper, neural precursor cell expressed, developmentally down-regulated gene 4-like antikoerper, NEDD4L antikoerper, LOC776799 antikoerper, nedd4l.S antikoerper, Nedd4l antikoerper
    Hintergrund
    This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel, ENaC. Single nucleotide polymorphisms in this gene may be associated with essential hypertension.
    Pathways
    Negative Regulation of Transporter Activity
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