ALKBH2 Antikörper

Produktnummer ABIN2422380

Produktdetails anti-ALKBH2 Antikörper

Target: ALKBH2 (AlkB, Alkylation Repair Homolog 2 (ALKBH2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ALKBH2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human ALKBH2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.3 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Konservierungsmittel: Sodium azide

Handhabung: Avoid freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ALKBH2

Target: ALKBH2 (AlkB, Alkylation Repair Homolog 2 (ALKBH2))

Andere Bezeichnung: ALKBH2 (ALKBH2 Produkte)

Synonyme: si:dkey-65b12.2 antikoerper, ABH2 antikoerper, 9530023G02 antikoerper, AU016977 antikoerper, Abh2 antikoerper, mABH2 antikoerper, RGD1306377 antikoerper, alkB homolog 2, alpha-ketoglutarate dependent dioxygenase antikoerper, alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase antikoerper, ALKBH2 antikoerper, alkbh2 antikoerper, Alkbh2 antikoerper

Hintergrund: The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 and ALKBH3 are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine. Dioxygenase that repairs alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. Can also repair alkylated DNA containing 1-ethenoadenine (in vitro). Has strong preference for double-stranded DNA. Has low efficiency with single-stranded substrates. Requires molecular oxygen, alpha-ketoglutarate and iron.

Molekulargewicht: Calculated MW: 29 kDa

Pathways: DNA Reparatur