MEK1 Antikörper (pSer218)

Produktnummer ABIN228872

Der Kaninchen-Polyklonal Anti-MEK1-Antikörper wurde für WB validiert. Er ist geeignet zum Nachweis von MEK1 in Proben aus Human, Maus und Ratte. }

Kurzübersicht für MEK1 Antikörper (pSer218) (ABIN228872)

Target: MEK1 (MAP2K1) (Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MEK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MEK1 Antikörper

Bindungsspezifität: pSer218

Spezifität: Recognizes human MEK 1 and MEK 2, when phosphorylated at serine 218 and 222. MEK 1 and MEK 2 are also known as MAP2K1 and MAP2K2, respectively. Species cross-reactivity: mouse. Species sequence homology: rat, bovine, canine, chicken, xenopus, zebrafish, monkey.

Aufreinigung: Affinity purified

Immunogen: Synthetic phosphopeptide corresponding to an amino acid sequence which includes phosphorylated serine 218 and 222 within MEK1 and 2.

Type of Immunogen: Synthetic phospho-peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Approved: WB (1:1000)

Usage: Suitable for use in Western Blot. Western Blot: 1:1000. Recognizes a band of ~45kD in Western Blots of serum stimulated NIH3T3 cell lysates. Positive control: NIH 3T3 cell lysate.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: 10 mM HEPES,  pH 7.5, 0.01 % BSA, 0.1 % sodium azide, 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Details zu MEK1

Target: MEK1 (MAP2K1) (Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))

Andere Bezeichnung: MAP2K1 / MEK1

Hintergrund: Name/Gene ID: MAP2K1
Subfamily: MAP2K
Family: Protein Kinase

Synonyms: MAP2K1, ERK activator kinase 1, MAPK/ERK kinase 1, MAPKK 1, MKK1, PRKMK1, MEK 1, MAP kinase kinase 1, MAPKK1, MEK1

Gen-ID: 5604

UniProt: Q02750

Pathways: MAPK Signalweg, RTK Signalweg, Interferon-gamma Pathway, Fc-epsilon Rezeptor Signalübertragung, Neurotrophin Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades, Autophagie, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling