PDE1C Antikörper (C-Term)

Produktnummer ABIN213547

Produktdetails anti-PDE1C Antikörper

Target: PDE1C (phosphodiesterase 1C, Calmodulin-Dependent 70kDa (PDE1C))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Fledermaus, Hamster, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDE1C Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Marke: IHC-plus™

Spezifität: Human PDE1C. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Homologie: Percent identity with other species by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Bovine, Dog, Bat, Hamster, Elephant, Panda, Horse, Rabbit (100%) Opossum (88%).

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic 16 amino acid peptide from C-terminus of human PDE1C. Percent identity with other species by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Bovine, Dog, Bat, Hamster, Elephant, Panda, Horse, Rabbit (100%), Opossum (88%).

Type of Immunogen: Synthetic peptide

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-P (5 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5 μg/mL.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS, less than 0.1 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu PDE1C

Target: PDE1C (phosphodiesterase 1C, Calmodulin-Dependent 70kDa (PDE1C))

Andere Bezeichnung: PDE1C (PDE1C Produkte)

Synonyme: CG14940 antikoerper, CG14942 antikoerper, CG14943 antikoerper, CG14944 antikoerper, CG31757 antikoerper, CG31758 antikoerper, CG42325 antikoerper, CG44007 antikoerper, Dmel\\CG44007 antikoerper, Dmel_CG14940 antikoerper, Dmel_CG14943 antikoerper, Dmel_CG14944 antikoerper, Dmel_CG31757 antikoerper, Dmel_CG31758 antikoerper, Dmel_CG42325 antikoerper, PDE1C antikoerper, PDE1c antikoerper, GB13690 antikoerper, Hcam3 antikoerper, Phosphodiesterase 1c antikoerper, phosphodiesterase 1C antikoerper, calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A antikoerper, calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C antikoerper, phosphodiesterase 1C, calmodulin-dependent b antikoerper, Pde1c antikoerper, PDE1C antikoerper, LOC724389 antikoerper, LOC100019026 antikoerper, pde1cb antikoerper

Hintergrund: Name/Gene ID: PDE1C
Subfamily: PDE - cAMP/cGMP dual-specific, Ca/Calmodulin-dependent
Family: Phosphodiesterase

Synonyms: PDE1C, HCam-3, Hcam3, Phosphodiesterase 1c, Cam-PDE 1C

Gen-ID: 5137

Pathways: EGFR Signaling Pathway, Neurotrophin Signalübertragung, Negative Regulation of Hormone Secretion, cAMP Metabolic Process, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma