FLT3LG Antikörper

Produktnummer ABIN205922

Produktdetails anti-FLT3LG Antikörper

Target: FLT3LG (Fms-Related tyrosine Kinase 3 Ligand (FLT3LG))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FLT3LG Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Functional Studies (Func)

Spezifität: Recognizes the ubiquitously expressed human growth factor Flt3-Ligand (Flt3L), a 235aa type I transmembrane glycoprotein which regulates the proliferation of early hematopoietic cells. Flt3L exists in both a membrane-bound and proteolytically cleaved soluble isoform, both of which are biologically active, and initiates cell proliferation/ differentiation signalling in co-operation with other colony stimulating factors (CSFs) and interleukins, by binding to and activating the tyrosine kinase receptor Flt3 (FLT3R), expressed highly by hematopoietic progenitor cells and stem cells.

Aufreinigung: Purified

Immunogen: Recombinant human Flt3-Ligand.

Type of Immunogen: Recombinant protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Approved: ELISA (0.5 μg/mL), Func (0.25 - 0.75 μg/mL), WB (0.1 - 0.2 μg/mL)

Usage: ELISA: May be used in an indirect ELISA system or as a capture antibody in a sandwich ELISA for human Flt3L .

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Distilled Water. For long term storage the addition of 0.09 % sodium azide is recommended. For functional studies do not add azide.

Konzentration: Lot specific

Buffer: Lyophilized, PBS,  pH 7.4.

Details zu FLT3LG

Target: FLT3LG (Fms-Related tyrosine Kinase 3 Ligand (FLT3LG))

Andere Bezeichnung: FLT3LG / Flt3 Ligand (FLT3LG Produkte)

Synonyme: Flt3lg antikoerper, Ly72L antikoerper, FL antikoerper, FLT3L antikoerper, Vegfr3 antikoerper, fms related tyrosine kinase 3 ligand antikoerper, FMS-like tyrosine kinase 3 ligand antikoerper, fms-related tyrosine kinase 4 antikoerper, fms-related tyrosine kinase 3 ligand antikoerper, FLT3LG antikoerper, Flt3l antikoerper, Flt4 antikoerper, Flt3lg antikoerper

Hintergrund: Name/Gene ID: FLT3LG

Synonyms: FLT3LG, FL, Flt3 ligand, FLT3L, SL cytokine

Gen-ID: 2323

Pathways: RTK Signalweg