NR1H4 Antikörper (AA 1-476) (HRP)

Produktnummer ABIN1991557

Produktdetails anti-NR1H4 Antikörper (HRP)

Target: NR1H4 (Nuclear Receptor Subfamily 1, Group H, Member 4 (NR1H4))

Bindungsspezifität: AA 1-476

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NR1H4 Antikörper ist konjugiert mit HRP

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Bile acid receptor protein (1-476AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin^TM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze.
Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu NR1H4

Target: NR1H4 (Nuclear Receptor Subfamily 1, Group H, Member 4 (NR1H4))

Andere Bezeichnung: NR1H4 (NR1H4 Produkte)

Synonyme: zgc:110190 antikoerper, zgc:92742 antikoerper, NR1H4 antikoerper, BAR antikoerper, FXR antikoerper, HRR-1 antikoerper, HRR1 antikoerper, RIP14 antikoerper, AI957360 antikoerper, Fxr antikoerper, Rxrip14 antikoerper, nuclear receptor subfamily 1, group H, member 5 S homeolog antikoerper, nuclear receptor subfamily 1, group H, member 4 antikoerper, nuclear receptor subfamily 1 group H member 4 antikoerper, nr1h5.S antikoerper, nr1h4 antikoerper, NR1H4 antikoerper, Nr1h4 antikoerper

Hintergrund:

Background: Ligand-activated transcription factor. Receptor for bile acids such as chenodeoxycholic acid, lithocholic acid and deoxycholic acid. Represses the transcription of the cholesterol 7-alpha-hydroxylase gene (CYP7A1) through the induction of NR0B2 or FGF19 expression, via two distinct mechanisms. Activates the intestinal bile acid-binding protein (IBABP). Activates the transcription of bile salt export pump ABCB11 by directly recruiting histone methyltransferase CARM1 to this locus.

Aliases: BAR antibody, Bile acid receptor antibody, Farnesoid X activated receptor antibody, Farnesoid X receptor antibody, Farnesoid X-activated receptor antibody, Farnesol receptor HRR 1 antibody, Farnesol receptor HRR-1 antibody, Farnesol receptor HRR1 antibody, FXR antibody, HRR 1 antibody, HRR1 antibody, NR1H4 antibody, NR1H4_HUMAN antibody, Nuclear receptor subfamily 1 group H member 4 antibody, Retinoid X receptor interacting protein 14 antibody, Retinoid X receptor-interacting protein 14 antibody, RIP 14 antibody, RIP14 antibody, RXR interacting protein 14 antibody, RXR-interacting protein 14 antibody

UniProt: Q96RI1

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Carbohydrate Metabolic Process