Western Blot: 1: 500approx. 1: 1000. Immunohistochemistry: 1: 50approx. 1: 100. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
1.0 mg/mL
Buffer
PBS (without Mg2+ and Ca2+), pH 7.4 containing 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
-20 °C
Target
HSP90AB1
(Heat Shock Protein 90kDa alpha (Cytosolic), Class B Member 1 (HSP90AB1))
D6S182 antikoerper, HSP84 antikoerper, HSP90B antikoerper, HSPC2 antikoerper, HSPCB antikoerper, GRP94 antikoerper, TRA1 antikoerper, hsp90b antikoerper, 90kDa antikoerper, AL022974 antikoerper, C81438 antikoerper, Hsp84 antikoerper, Hsp84-1 antikoerper, Hsp90 antikoerper, Hspcb antikoerper, Hsp70 antikoerper, Hsp70-1 antikoerper, Hsp70.1 antikoerper, hsp68 antikoerper, HSP90-BETA antikoerper, hsp90beta antikoerper, wu:fa29f01 antikoerper, wu:fa91e11 antikoerper, wu:fd59e11 antikoerper, wu:gcd22h07 antikoerper, HSP90 antikoerper, heat shock protein 90 alpha family class B member 1 antikoerper, heat shock protein 90 beta family member 1 antikoerper, Heat Shock Protein 90, endoplasmic reticulum antikoerper, heat shock protein 90B antikoerper, heat shock protein 90 alpha (cytosolic), class B member 1 antikoerper, heat shock protein 1B antikoerper, heat shock protein 90kDa alpha family class B member 1 S homeolog antikoerper, heat shock protein 90, alpha (cytosolic), class B member 1 antikoerper, HSP90AB1 antikoerper, HSP90B1 antikoerper, HSP90B antikoerper, hsp90ab1 antikoerper, Hsp90ab1 antikoerper, Hspa1b antikoerper, hsp90ab1.S antikoerper
Hintergrund
In mammalian cells there are at least two Hsp90 isoforms, Hsp90a and Hsp90b which are encoded by separate genes. These ubiquitous and highly conserved proteins account for 1-2 % of all cellular proteins in most cells. Hsp90 is part of the cells powerful network of chaperones to fight the deleterious consequences of protein unfolding caused by nonphysiological conditions. However, in the absence of stress, Hsp90 is a necessary component of fundamental cellular processes such as hormone signaling and cell cycle control. In this context several key regulatory proteins such as steriod receptors, cell cycle kinases involved in signal transduction and p53 have been identified as substrates of Hsp90. It has been suggested that Hsp90 acts as a capacitor for morphological evolution by buffering widespread variation, which may affect morphogenic pathways.Synonyms: HSP84, HSP90B, HSPC2, HSPCB, Heat shock 84 kDa, Heat shock protein HSP 90-beta