HSP90AB1 Antikörper (Internal Region)
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- Target Alle HSP90AB1 Antikörper anzeigen
- HSP90AB1 (Heat Shock Protein 90kDa alpha (Cytosolic), Class B Member 1 (HSP90AB1))
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser HSP90AB1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- Kreuzreaktivität
- Rhesusaffen, Rind (Kuh)
- Kreuzreaktivität (Details)
- Rhesus Monkey (100 %), Bovine (100 %)
- Produktmerkmale
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Rabbit Polyclonal antibody to HSP90 beta (heat shock protein 90 kDa alpha (cytosolic), class B member 1)
HSP90 beta antibody [N2C2], Internal - Aufreinigung
- Affinity purified by Protein A.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human HSP90 beta. The exact sequence is proprietary.
- Isotyp
- IgG
- Top Product
- Discover our top product HSP90AB1 Primärantikörper
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- Applikationshinweise
- Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
- Kommentare
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Positive Control: HeLaS3
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 5.43 mg/mL
- Buffer
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
- Konservierungsmittel
- Thimerosal (Merthiolate)
- Vorsichtsmaßnahmen
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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PGRMC2 is an intracellular haem chaperone critical for adipocyte function." in: Nature, Vol. 576, Issue 7785, pp. 138-142, (2020) (PubMed).
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PGRMC2 is an intracellular haem chaperone critical for adipocyte function." in: Nature, Vol. 576, Issue 7785, pp. 138-142, (2020) (PubMed).
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- Target
- HSP90AB1 (Heat Shock Protein 90kDa alpha (Cytosolic), Class B Member 1 (HSP90AB1))
- Andere Bezeichnung
- HSP90 beta (HSP90AB1 Produkte)
- Synonyme
- D6S182 antikoerper, HSP84 antikoerper, HSP90B antikoerper, HSPC2 antikoerper, HSPCB antikoerper, GRP94 antikoerper, TRA1 antikoerper, hsp90b antikoerper, 90kDa antikoerper, AL022974 antikoerper, C81438 antikoerper, Hsp84 antikoerper, Hsp84-1 antikoerper, Hsp90 antikoerper, Hspcb antikoerper, Hsp70 antikoerper, Hsp70-1 antikoerper, Hsp70.1 antikoerper, hsp68 antikoerper, HSP90-BETA antikoerper, hsp90beta antikoerper, wu:fa29f01 antikoerper, wu:fa91e11 antikoerper, wu:fd59e11 antikoerper, wu:gcd22h07 antikoerper, HSP90 antikoerper, heat shock protein 90 alpha family class B member 1 antikoerper, heat shock protein 90 beta family member 1 antikoerper, Heat Shock Protein 90, endoplasmic reticulum antikoerper, heat shock protein 90B antikoerper, heat shock protein 90 alpha (cytosolic), class B member 1 antikoerper, heat shock protein 1B antikoerper, heat shock protein 90kDa alpha family class B member 1 S homeolog antikoerper, heat shock protein 90, alpha (cytosolic), class B member 1 antikoerper, HSP90AB1 antikoerper, HSP90B1 antikoerper, HSP90B antikoerper, hsp90ab1 antikoerper, Hsp90ab1 antikoerper, Hspa1b antikoerper, hsp90ab1.S antikoerper
- Hintergrund
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HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. There are 2 major cytosolic HSP90 proteins, HSP90AA1 (MIM 140571), an inducible form, and HSP90AB1, a constitutive form. Other HSP90 proteins are found in endoplasmic reticulum (HSP90B1, MIM 191175) and mitochondria (TRAP1, MIM 606219) (Chen et al., 2005 [PubMed 16269234]).[supplied by OMIM]
Cellular Localization: Cytoplasm , Melanosome - Molekulargewicht
- 83 kDa
- Gen-ID
- 3326
- Pathways
- Regulation of Cell Size
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