MYL2 Antikörper (AA 16-20)

Produktnummer ABIN197362

Produktdetails anti-MYL2 Antikörper

Target: MYL2 (Myosin, Light Chain 2, Regulatory, Cardiac, Slow (MYL2))

Bindungsspezifität: AA 16-20

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MYL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Spezifität: This antibody AP02680PU detects endogenous levels of total Myosin Light Chain 2 protein.

Aufreinigung: Immunoaffinity Chromatography using epitope-specific immunogen.

Immunogen: Peptide sequence around amino acids 16~20 (A-T-S-N-V) derived from Human Myosin Light Chain 2 Protein.

Anwendungsinformationen

Applikationshinweise: Western blot: 1/500-1/1000. Immunofluorescence: 1/100-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody (in aliquots) at -20 °C.

Details zu MYL2

Target: MYL2 (Myosin, Light Chain 2, Regulatory, Cardiac, Slow (MYL2))

Andere Bezeichnung: Myosin Light Chain 2 (MYL2) (MYL2 Produkte)

Synonyme: CMH10 antikoerper, MLC2 antikoerper, 2410014J02Rik antikoerper, MLC-2 antikoerper, Mlc2 antikoerper, MLC-2v antikoerper, Mlc2v antikoerper, Mylpc antikoerper, Mlc-2 antikoerper, myl2 antikoerper, zgc:136848 antikoerper, XMLC2 antikoerper, cmh10 antikoerper, mlc2 antikoerper, G2 antikoerper, MLC-2A antikoerper, MLC2V antikoerper, myosin light chain 2 antikoerper, myosin light chain, phosphorylatable, fast skeletal muscle antikoerper, myosin, light polypeptide 2, regulatory, cardiac, slow antikoerper, myosin, light chain 2b, regulatory, cardiac, slow antikoerper, myosin light chain 2 S homeolog antikoerper, myosin, light chain 2, regulatory, cardiac, slow antikoerper, MYL2 antikoerper, Mylpf antikoerper, Myl2 antikoerper, myl2b antikoerper, myl2.S antikoerper

Hintergrund: Myosin light chain 2 (MYL2) encodes the regulatory light chain associated with cardiac myosin beta heavy chain. It is an important protein involved in the regulation of myosin ATPase activity in smooth muscle and Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. Mutations in MYL2 are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy.Synonyms: MLC-2, MLC-2v, Myosin regulatory light chain 2 ventricular/cardiac muscle isoform

Gen-ID: 4633

NCBI Accession: NP_000423

UniProt: P10916

Pathways: Myometrial Relaxation and Contraction