LZTS2 Antikörper (N-Term)

Produktnummer ABIN1888112

Produktdetails anti-LZTS2 Antikörper

Target: LZTS2 (Leucine Zipper, Putative Tumor Suppressor 2 (LZTS2))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LZTS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität (Details): LZTS2 antibody is predicted to not cross-react with other LZTS family members

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 19 amino acid peptide near the amino terminus of human LZTS2.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu LZTS2

Target: LZTS2 (Leucine Zipper, Putative Tumor Suppressor 2 (LZTS2))

Andere Bezeichnung: LZTS2 (LZTS2 Produkte)

Synonyme: lapser1 antikoerper, MGC89253 antikoerper, si:dkey-250a11.1 antikoerper, LAPSER1 antikoerper, BC014695 antikoerper, mKIAA1813 antikoerper, Lapser1 antikoerper, leucine zipper, putative tumor suppressor 2 antikoerper, leucine zipper tumor suppressor 2 antikoerper, leucine zipper, putative tumor suppressor 2a antikoerper, leucine zipper, putative tumor suppressor 2 S homeolog antikoerper, lzts2 antikoerper, LZTS2 antikoerper, lzts2a antikoerper, Lzts2 antikoerper, lzts2.S antikoerper

Hintergrund: The leucine zipper putative tumor suppressor 2 (LZTS2, also known as LAPSER1), a member of the LZTS family, is a negative regulator of the Wnt signaling pathway.It represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin.LZTS2 is involved in cytokinesis and regulates katanin-mediated microtubule severing and release from the centrosome.LZTS2 may negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon.LZTS2 is highly expressed in testis and prostate, but it is deleted in multiple cancers, including prostate tumors, suggesting that LZTS2 acts as a potential tumor suppressor.
Synonyms: Leucine zipper putative tumor suppressor 2, LAPSER1

NCBI Accession: NP_115805